Microscopy and Histopathology CoLab

Overview of Services

The Microscopy and Histopathology CoLab is an institutional shared research resource at SCRI that provides access to advanced cutting-edge imaging technology and tissue processing services in a collaborative manner for investigators at SCRI that is cost effective and equitable.

Available microscopes in the CoLab include a Zeiss Microscopy LSM 900 confocal microscope with 405, 488, 561, and 640 nm laser lines, and a Zeiss Microscopy LSM 980 confocal microscope with 405, 445, 488, 514, 561, 594, 639, and 730 nm laser lines and NIR detectors. The two confocal microscopes are equipped with Airyscan 2 technology, which allows for super resolution imaging by harnessing an array of 32 area detector elements to collect additional information by reducing the signal to noise ratio. Microscopy services also include training and support with image visualization and analysis.

Coming soon:

Histopathology services provided by the CoLab are planned to include tissue processing, embedding, sectioning, basic staining as well as immunohistochemistry. Consultation on experimental set up, slide preparation and data analysis will also be available. Slide digitization services are provided using Zeiss Microscopy Axioscan 7 which has a capacity of up to 100 slides per scan using objectives that include 5x, 10x, 20x, and 40x magnification.

Stay tuned for more information on the availability of histology and IHC services.

Leadership

Aaron Larson, MSB
Director of Operations, Shared Research Resources

425-299-1829

Aarya Vaikakkara Chithran, PhD
Research Scientist II

Location and hours of operation

Monday-Friday 9:00 am - 5:00 pm  

Microscopy: 1900 9th Ave, JMB 566A  
Histopathology:1920 Terry Ave, Building Cure
Slide Scanning: 1100 Olive Way, Suite 100

 

Contacts

Name Role Phone Email Location
Aaron Larson, MSB
Director of Operations, Shared Research Resources
 
425-299-1829
 
aaron.larson@seattlechildrens.org
 
JMB 712
 
Aarya Vaikakkara Chithran, PhD
Research Scientist II
 
206-884-4655
 
aarya.vaikakkarachithran@seattlechildrens.org
 
JMB 713